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細(xì)胞表面趨化因子受體5重組兔單克隆抗體
  • 產(chǎn)品貨號：
    BN42162R
  • 中文名稱：
    細(xì)胞表面趨化因子受體5重組兔單克隆抗體
  • 英文名稱：
    Rabbit anti-CXCR5 Monoclonal antibody
  • 品牌：
    Biorigin

  • 貨號

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  • BN42162R-50ul

    50ul

    ￥2020.00

    交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：WB,IHC-P,IHC-F

  • BN42162R-100ul

    100ul

    ￥3240.00

    交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：WB,IHC-P,IHC-F

產(chǎn)品描述

英文名稱CXCR5
中文名稱細(xì)胞表面趨化因子受體5重組兔單克隆抗體
別    名BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; Cxcr5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15.  
研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  趨化因子  G蛋白偶聯(lián)受體  b-淋巴細(xì)胞  G蛋白信號  
抗體來源Rabbit
克隆類型Monoclonal
克 隆 號3B7
交叉反應(yīng)Human, Mouse, Rat, 
產(chǎn)品應(yīng)用WB=1:500-1000 IHC-P=1:50-200 IHC-F=1:50-200 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原Recombinant human CXCR5: 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen.

Function:
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expression in mature B-cells and Burkitt lymphoma cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P32302

Gene ID:
643

Database links:

Entrez Gene: 643 Human

Entrez Gene: 12145 Mouse

Entrez Gene: 29363 Rat

Omim: 601613 Human

SwissProt: P32302 Human

SwissProt: Q04683 Mouse

SwissProt: P34997 Rat

Unigene: 113916 Human

Unigene: 490637 Mouse

Unigene: 6246 Mouse

Unigene: 120732 Rat

Unigene: 127121 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications