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癌基因RAS相關蛋白Rab4A抗體
  • 產(chǎn)品貨號：
    BN41936R
  • 中文名稱：
    癌基因RAS相關蛋白Rab4A抗體
  • 英文名稱：
    Rabbit anti-RAB4 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41936R-50ul

    50ul

    ￥1486.00

    交叉反應：Mouse,Human(predicted:GuineaPig,Sheep,Rabbit,Horse,Cow,Pig,Dog,Chicken,Rat) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41936R-100ul

    100ul

    ￥2360.00

    交叉反應：Mouse,Human(predicted:GuineaPig,Sheep,Rabbit,Horse,Cow,Pig,Dog,Chicken,Rat) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41936R-200ul

    200ul

    ￥3490.00

    交叉反應：Mouse,Human(predicted:GuineaPig,Sheep,Rabbit,Horse,Cow,Pig,Dog,Chicken,Rat) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱RAB4
中文名稱癌基因RAS相關蛋白Rab4A抗體
別    名HRES 1 / RAB4; Oncogene RAB4; OTTHUMP00000042824; Rab 4; RAB 4A; RAB4 member RAS oncogene family; RAB4A; RAB4A member RAS oncogene family; RAB4A_HUMAN; Ras related protein Rab 4A; Ras related protein Rab4A; Ras-related protein Rab-4A.  
研究領域腫瘤  細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  G蛋白偶聯(lián)受體  細胞類型標志物  G蛋白信號  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
細胞定位細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RAB4:21-120/218 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).

Function:
Protein transport. Probably involved in vesicular traffic (By similarity).

Subunit:
Interacts with SGSM1, SGSM2 and SGSM3 (By similarity). Interacts with RAB11FIP1, RABEP1, ZFYVE20 and RUFY1. Interacts (membrane-bound form) with NDRG1; the interaction involves NDRG1 in vesicular recycling of E-cadherin.

Subcellular Location:
Membrane; Peripheral membrane protein. Cytoplasm. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.

Post-translational modifications:
Phosphorylated by CDK1 kinase during mitosis.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
P20338

Gene ID:
5867

Database links:

Entrez Gene: 5867 Human

Entrez Gene: 19341 Mouse

Entrez Gene: 25532 Rat

Omim: 179511 Human

SwissProt: P20338 Human

SwissProt: P56371 Mouse

SwissProt: P05714 Rat

Unigene: 296169 Human

Unigene: 9221 Mouse

Unigene: 3016 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.