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S腺苷L-同型半胱氨酸水解酶抗體
  • 產(chǎn)品貨號：
    BN41919R
  • 中文名稱：
    S腺苷L-同型半胱氨酸水解酶抗體
  • 英文名稱：
    Rabbit anti-SAHH Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41919R-50ul

    50ul

    ￥1486.00

    交叉反應：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41919R-100ul

    100ul

    ￥2360.00

    交叉反應：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41919R-200ul

    200ul

    ￥3490.00

    交叉反應：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱SAHH
中文名稱S腺苷L-同型半胱氨酸水解酶抗體
別    名Adenosylhomocysteinase; AdoHcyase; ahcY; S adenosyl L homocysteine hydrolase; S adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; SAHH_HUMAN.  


研究領域腫瘤  細胞生物  免疫學  信號轉導  轉錄調節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量48kDa
細胞定位細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SAHH:25-125/432 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Function:
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Subunit:
Homotetramer.

Subcellular Location:
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

DISEASE:
Defects in AHCY are the cause of hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) [MIM:613752]. A metabolic disorder characterized by hypermethioninemia associated with failure to thrive, mental and motor retardation, facial dysmorphism with abnormal hair and teeth, and myocardiopathy.

Similarity:
Belongs to the adenosylhomocysteinase family.

SWISS:
P23526

Gene ID:
191

Database links:

Entrez Gene: 191 Human

Entrez Gene: 269378 Mouse

Entrez Gene: 29443 Rat

Omim: 180960 Human

SwissProt: P23526 Human

SwissProt: P50247 Mouse

SwissProt: P10760 Rat

Unigene: 388004 Human

Unigene: 330692 Mouse

Unigene: 371964 Mouse

Unigene: 5878 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.