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可溶性蘋果酸脫氫酶抗體
  • 產(chǎn)品貨號(hào):
    BN41886R
  • 中文名稱:
    可溶性蘋果酸脫氫酶抗體
  • 英文名稱:
    Rabbit anti-MDH1 Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號(hào)

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  • BN41886R-50ul

    50ul

    ¥1486.00

    交叉反應(yīng):Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41886R-100ul

    100ul

    ¥2360.00

    交叉反應(yīng):Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41886R-200ul

    200ul

    ¥3490.00

    交叉反應(yīng):Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱MDH1
中文名稱可溶性蘋果酸脫氫酶抗體
別    名Cytosolic malate dehydrogenase; Malate dehydrogenase 1, NAD (soluble); MDHA; MDHs; Soluble malate dehydrogenase; Malate dehydrogenase; Diiodophenylpyruvate reductase; Malate dehydrogenase 1; Malate dehydrogenase 1 NAD (soluble); Malate dehydrogenase 2; Malate dehydrogenase cytoplasmic; Malate dehydrogenase 2 NAD (mitochondrial); MDH 1; MDH 2; MDH; MDH1; MDH2; MDHA; MDHm; MDHs; MMDH; Mor 1; Mor 2; Mor1; MOR2; cytoplasmic; MDH s; mdh1; MDHC_HUMAN; MGC:1375; SMDH; Soluble malate dehydrogenase.   




研究領(lǐng)域腫瘤  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/Test IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量36kDa
細(xì)胞定位細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MDH1:265-334/334 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. Malate dehydrogenase 1 (MDH1) is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
ISGylated.
Acetylation at Lys-118 dramatically enhances enzymatic activity and promotes adipogenic differentiation.

Similarity:
Belongs to the LDH/MDH superfamily. MDH type 2 family.

SWISS:
P40925

Gene ID:
4190

Database links:

Entrez Gene: 4190 Human

Entrez Gene: 17449 Mouse

Entrez Gene: 24551 Rat

Omim: 154200 Human

SwissProt: P40925 Human

SwissProt: P14152 Mouse

SwissProt: O88989 Rat

Unigene: 526521 Human

Unigene: 212703 Mouse

Unigene: 13492 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.