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整合素αVβ1抗體
  • 產(chǎn)品貨號(hào)：
    BN41770R
  • 中文名稱：
    整合素αVβ1抗體
  • 英文名稱：
    Rabbit anti-Integrin Alpha V + Beta 1 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41770R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用：WB,IHC-P,Flow-Cyt,ELISA

  • BN41770R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用：WB,IHC-P,Flow-Cyt,ELISA

  • BN41770R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用：WB,IHC-P,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Integrin Alpha V + Beta 1
中文名稱整合素αVβ1抗體
別    名fibronectin receptor alpha; ITGAV; CD51; DKFZp686A08142; MSK8; Msk 8; VNR; similar to Integrin alpha-V precursor; Vitronectin receptor subunit alpha; CD51 antigen; HGNC; Vitronectin receptor alpha polypeptide; Vitronectin receptor alpha polypeptide antigen CD51; VNRA.  



研究領(lǐng)域細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞膜受體  細(xì)胞粘附分子  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 Flow-Cyt=1μg /test （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量114kDa
細(xì)胞定位細(xì)胞漿 分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic Mixed peptides 915-948/1048(human Integrin αV)+ 21-70/798(human Integrin β1): 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells.
Integrin alpha 5 belongs to the integrin alpha chain family. It contains seven FG-GAP repeats.
Integrin beta 1 belongs to the integrin beta chain family. It contains one VWFA domain.
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein se
ems to enhance angiogenesis in Kaposi's sarcoma lesions.

Function:
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Subcellular Location:
Membrane.

Similarity:
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.

SWISS:
P06756

Gene ID:
3685

Database links:

Entrez Gene: 3685 Human

Omim: 193210 Human

SwissProt: P06756 Human

Unigene: 436873 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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