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抑制素βB/Inhibin β B抗體
  • 產(chǎn)品貨號：
    BN41753R
  • 中文名稱：
    抑制素βB/Inhibin β B抗體
  • 英文名稱：
    Rabbit anti-Inhibin beta B Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41753R-50ul

    50ul

    ￥1486.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Sheep,GuineaPig) 推薦應用：WB,IHC-P,IHC-F,ELISA

  • BN41753R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Sheep,GuineaPig) 推薦應用：WB,IHC-P,IHC-F,ELISA

  • BN41753R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Sheep,GuineaPig) 推薦應用：WB,IHC-P,IHC-F,ELISA

產(chǎn)品描述

英文名稱Inhibin beta B
中文名稱抑制素βB/Inhibin β B抗體
別    名MGC157939; Activin A; Activin AB alpha polypeptide; Activin AB; Activin AB beta polypeptide; Activin B; Activin beta A chain; Activin beta B chain; ActivinA; ActivinAB; ActivinB; EDF; Erythroid differentiation protein; follicle stimulating hormone releasing protein; FRP; FSH releasing factor; FSH releasing protein; INHBA; INHBB; Inhibin; Inhibin beta 1; Inhibin beta 2; Inhibin beta A; Inhibin beta A chain; Inhibin beta A subunit; Inhibin beta B; Inhibin beta B chain; Inhibin beta B subunit;   
研究領域神經(jīng)生物學  信號轉導  生長因子和激素  轉錄調節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Sheep, Guinea Pig, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量13/45kDa
細胞定位分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Inhibin beta B:251-350/407 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq].

Subcellular Location:
Secreted.

Similarity:
Belongs to the TGF-beta family.

SWISS:
P09529

Gene ID:
3625

Database links:

Entrez Gene: 3625 Human

Entrez Gene: 16324 Mouse

Entrez Gene: 25196 Rat

Omim: 147390 Human

SwissProt: P09529 Human

SwissProt: Q04999 Mouse

SwissProt: P17491 Rat

Unigene: 1735 Human

Unigene: 3092 Mouse

Unigene: 35074 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

抑制素是轉化生長因子TGFβ超級家族，主要由雌性動物卵巢顆粒細胞和雄性動物睪丸的Sertoli細胞分泌.研究表明,抑制素具有內分泌和旁分泌物的作用:既可通過復雜的反饋機理,調節(jié)體液FSH水平。












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