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催產(chǎn)素受體(縮宮素受體)抗體
  • 產(chǎn)品貨號：
    BN41686R
  • 中文名稱：
    催產(chǎn)素受體(縮宮素受體)抗體
  • 英文名稱：
    Rabbit anti-Oxytocin R Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41686R-50ul

    50ul

    ￥1486.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推薦應用：WB,IHC-P,ELISA

  • BN41686R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推薦應用：WB,IHC-P,ELISA

  • BN41686R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推薦應用：WB,IHC-P,ELISA

產(chǎn)品描述

英文名稱Oxytocin R
中文名稱催產(chǎn)素受體(縮宮素受體)抗體
別    名Oxytocin R; OT R; OT-R; OTR 1; OTR; OTR1; OXT R; OXTR; Oxytocin receptor; OXYR_HUMAN.  
研究領域神經(jīng)生物學  生長因子和激素  細胞膜受體  內(nèi)分泌病  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量43kDa
細胞定位細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse oxytocin receptor:325-388/388 <Cytoplasmic>
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. Oxytocin receptor has been reported in breast, central nervous system, heart, ovary, placenta, prostate, salivary gland, testis, uterus, and vessel.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

SWISS:
P97926

Gene ID:
18430

Database links:

Entrez Gene: 281371 Cow

Entrez Gene: 5021 Human

Entrez Gene: 18430 Mouse

Entrez Gene: 397092 Pig

Entrez Gene: 25342 Rat

Omim: 167055 Human

SwissProt: P56449 Cow

SwissProt: P30559 Human

SwissProt: P97926 Mouse

SwissProt: P32306 Pig

SwissProt: P70536 Rat

SwissProt: Q28756 Sheep

Unigene: 2820 Human

Unigene: 333310 Mouse

Unigene: 6841 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OTR在人的子宮平滑肌細胞膜上有縮宮素受體，縮宮素引起子宮收縮的機制可能是通過激活縮宮素受體而實現(xiàn)的。經(jīng)研究發(fā)現(xiàn)，縮宮素受體在外周組織和中樞神經(jīng)系統(tǒng)內(nèi)均有分布?？s宮素與不同組織、細胞上的縮宮素受體結合，通過多種信號轉(zhuǎn)導途徑而發(fā)揮作用。