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內(nèi)皮素-1抗體
  • 產(chǎn)品貨號：
    BN41600R
  • 中文名稱：
    內(nèi)皮素-1抗體
  • 英文名稱：
    Rabbit anti-ET-1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41600R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep,GuineaPig) 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41600R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep,GuineaPig) 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41600R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Sheep,GuineaPig) 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱ET-1
中文名稱內(nèi)皮素-1抗體
別    名Endothelin-1; Big endothelin 1; EDN 1; EDN1; EDN1 protein; Endothelin1; ET 1; ET1; OTTHUMP00000039245; PPET1; Preproendothelin 1; Preproendothelin1.  
研究領(lǐng)域心血管  細胞生物  免疫學  神經(jīng)生物學  激酶和磷酸酶  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Sheep, Guinea Pig, )
產(chǎn)品應(yīng)用ELISA=1:5000-20000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量2.5kDa
細胞定位分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ET-1(CSCSSLMDKECVYFCHLDIIW Disulfide bridges C1-C15, C3-C11):53-73/202 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Function:
Endothelins are endothelium-derived vasoconstrictor peptides.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Similarity:
Belongs to the endothelin/sarafotoxin family.

SWISS:
P05305

Gene ID:
1906

Database links:

Entrez Gene: 1906 Human

Entrez Gene: 13614 Mouse

Entrez Gene: 24323 Rat

Omim: 131240 Human

SwissProt: P05305 Human

SwissProt: P22387 Mouse

SwissProt: P22388 Rat

Unigene: 511899 Human

Unigene: 713645 Human

Unigene: 10918 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

內(nèi)皮素(Endothelin-1,ET)是一種強的血管收縮劑，分為ET-1,ET-2,ET-3 三種,ET-1主要在內(nèi)皮細胞中表達,而ET-2和ET-3則主要在神經(jīng)系統(tǒng)中表達。ET具有廣泛的生物學作用，此抗體是針對內(nèi)皮素的活性片段（CSCSSLMDKECVYFCHLDIIW Disulfide bridges C1-C15, C3-C11）。













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