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骨鈣蛋白/骨鈣素抗體
  • 產(chǎn)品貨號：
    BN41538R
  • 中文名稱：
    骨鈣蛋白/骨鈣素抗體
  • 英文名稱：
    Rabbit anti-Osteocalcin Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41538R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Cow,Horse) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

  • BN41538R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Cow,Horse) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

  • BN41538R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Cow,Horse) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱Osteocalcin
中文名稱骨鈣蛋白/骨鈣素抗體
別    名Osteocalcin Propeptide; Osteocalcin; Osteocalcin precursor; Gamma-carboxyglutamic acid-containing protein; Bone Gla-protein; BGLAP; Bone gamma carboxyglutamate protein; BGLAP; BGP; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gla protein; Gamma carboxyglutamic acid containing protein; OC; PMF1; OSTCN_HUMAN.  



研究領(lǐng)域免疫學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量11kDa
細(xì)胞定位分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human BGP:21-80/100 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.

Function:
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.

Subcellular Location:
Secreted.

Post-translational modifications:
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.

Similarity:
Belongs to the osteocalcin/matrix Gla protein family.
Contains 1 Gla (gamma-carboxy-glutamate) domain.

SWISS:
P02818

Gene ID:
632

Database links:

Entrez Gene: 281646 Cow

Entrez Gene: 632 Human

Entrez Gene: 397530 Pig

Entrez Gene: 25295 Rat

Omim: 112260 Human

SwissProt: P02820 Cow

SwissProt: P02818 Human

SwissProt: Q8HYY9 Pig

SwissProt: P04640 Rat

Unigene: 654541 Human

Unigene: 9722 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

骨鈣素又稱骨γ-羧谷氨酸包含蛋白