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P物質(zhì)抗體
  • 產(chǎn)品貨號：
    BN41477R
  • 中文名稱：
    P物質(zhì)抗體
  • 英文名稱：
    Rabbit anti-Substance P Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

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  • BN41477R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Mouse,Rat,GuineaPig(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41477R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat,GuineaPig(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41477R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat,GuineaPig(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Substance P
中文名稱P物質(zhì)抗體
別    名Hs.2563; Neurokinin 1; Neurokinin 2; Neurokinin A; Neurokinin alpha; Neuromedin L; Neuropeptide gamma; NKA; NKNA; PPT; Protachykinin 1 precursor; Substance K; Substance P; TAC1; TAC2; Tachykinin 1; Tachykinin 2; Tachykinin precursor 1; Tachykinin1; TACI; TKN1_HUMAN.  



研究領(lǐng)域神經(jīng)生物學(xué)  新陳代謝  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat,  (predicted: Human, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量1.4/13kDa
細(xì)胞定位分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Substance P(RPKPQQFFGLM):58-68/129 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Subcellular Location:
Secreted.

Similarity:
Belongs to the tachykinin family.

SWISS:
P20366

Gene ID:
6863

Database links:

Entrez Gene: 6863 Human

Entrez Gene: 21333 Mouse

Entrez Gene: 24806 Rat

Omim: 162320 Human

SwissProt: P20366 Human

SwissProt: P41539 Mouse

SwissProt: P06767 Rat

Unigene: 2563 Human

UniProtKB/Swiss-Prot: P20366.1



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

P物質(zhì)（Substance P）是腦組織及消化道中發(fā)現(xiàn)的一種神經(jīng)遞質(zhì)肽。由130個氨基酸殘基組成，胃腸道中肌肉收縮的有力促進(jìn)劑，亦為強(qiáng)血管擴(kuò)張劑。
SP是一種腦腸肽，亦是最早發(fā)現(xiàn)的一種神經(jīng)肽，屬于速激肽家族成員，它廣泛分布于中樞及外周神經(jīng)系統(tǒng)，作為一種神經(jīng)遞質(zhì)或調(diào)質(zhì)參與疼痛、免疫、心血管等多種生理功能的調(diào)節(jié)。SP與其它的遞質(zhì)或調(diào)質(zhì)類似，能作用于多種類型的受體，速激肽家族有NK1、NK2、NK3三種受體，都能與SP結(jié)合，其中NK1與SP的結(jié)合能力最強(qiáng)而被稱為SP受體。













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