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產(chǎn)品規(guī)格
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BN41415R-100ul
100ul
¥2360.00
交叉反應(yīng):Human(predicted:Mouse,Rat,Pig,Cow,Rabbit,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41415R-200ul
200ul
¥3490.00
交叉反應(yīng):Human(predicted:Mouse,Rat,Pig,Cow,Rabbit,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
產(chǎn)品描述
英文名稱 | KCNE1L |
中文名稱 | 鉀離子通道蛋白家族成員1樣蛋白抗體 |
別 名 | AMME syndrome candidate gene 2 protein; AMMECR2 protein; Cardiac voltage gated potassium channel accessory subunit 5; KCNE1 like; KCNE5; Mink; MinK like protein; Potassium voltage gated channel subfamily E member 1 like protein; Potassium voltage gated channel, Isk related family, member 1 like; Voltage gated potassium channel accessory subunit 5; KCE1L_HUMAN. |
研究領(lǐng)域 | 心血管 神經(jīng)生物學(xué) 通道蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Pig, Cow, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:50-200 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 15kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KCNE1L:11-110/142 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
產(chǎn)品介紹 | KCNE1L belongs to the potassium channel KCNE family which represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Subcellular Location: Plasma membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta. DISEASE: Defects in KCNE1L are involved in Alport syndrome with mental retardation midface hypoplasia and elliptocytosis (ATS-MR) [MIM:300194]. A X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, deafness, mental retardation, midface hypoplasia and elliptocytosis. Similarity: Belongs to the potassium channel KCNE family. SWISS: Q9UJ90 Gene ID: 23630 Database links: Entrez Gene: 23630 Human Omim: 300328 Human SwissProt: Q9UJ90 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |