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環(huán)核苷酸磷酸二酯酶PDE3B抗體
  • 產(chǎn)品貨號：
    BN41341R
  • 中文名稱：
    環(huán)核苷酸磷酸二酯酶PDE3B抗體
  • 英文名稱：
    Rabbit anti-PDE3B Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價(jià)

    備注

  • BN41341R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41341R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Dog,Pig,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱PDE3B
中文名稱環(huán)核苷酸磷酸二酯酶PDE3B抗體
別    名5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodiesterase; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase B; Cyclic GMP-inhibited phosphodiesterase B; Cyclic nucleotide phosphodiesterase; HcGIP1; HcGIP1, rat, homolog of; Pde3b; PDE3B_HUMAN; Phosphodiesterase 3B cGMP inhibited.  
研究領(lǐng)域細(xì)胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量124kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PDE3B:451-550/1112 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.

Function:
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism.

Subcellular Location:
Membrane.

Tissue Specificity:
Abundant in adipose tissues.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.

SWISS:
Q13370

Gene ID:
5140

Database links:

Entrez Gene: 5140 Human

Entrez Gene: 18576 Mouse

Entrez Gene: 29516 Rat

Omim: 602047 Human

SwissProt: Q13370 Human

SwissProt: Q61409 Mouse

SwissProt: Q8CIX5 Mouse

SwissProt: Q63085 Rat

Unigene: 445711 Human

Unigene: 430730 Mouse

Unigene: 10322 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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