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GTP酶IMAP家族成員2抗體
  • 產(chǎn)品貨號(hào)：
    BN41313R
  • 中文名稱：
    GTP酶IMAP家族成員2抗體
  • 英文名稱：
    Rabbit anti-GIMAP2 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41313R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF

  • BN41313R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF

產(chǎn)品描述

英文名稱GIMAP2
中文名稱GTP酶IMAP家族成員2抗體
別    名GTPase, IMAP family member 2; HIMAP2; IMAP2; Immunity associated protein 2; GIMA2_HUMAN.  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng)Human, 
產(chǎn)品應(yīng)用IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量38kDa
細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GIMAP2:21-120/337 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP2 (GTPase IMAP family member 2), also known as IMAP2 (immunity-associated protein 2) or HIMAP2, is a 337 amino acid multi-pass membrane protein that is encoded by a gene located on human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

Function:
Monomer in the presence of bound GDP and in the absence of bound nucleotide. Homodimer in the presence of bound GTP. Can form linear oligomers.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential). Cytoplasm. Note=Detected on the surface of cytoplasmic lipid droplets.

Similarity:
Belongs to the IAN GTP-binding protein family.

SWISS:
Q9UG22

Gene ID:
26157

Database links:

Entrez Gene: 26157 Human

Omim: 608085 Human

SwissProt: Q9UG22 Human

Unigene: 647071 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.