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脈周蛋白1抗體（胃癌抗原蛋白Ga50）
  • 產(chǎn)品貨號：
    BN41281R
  • 中文名稱：
    脈周蛋白1抗體（胃癌抗原蛋白Ga50）
  • 英文名稱：
    Rabbit anti-PPHLN1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41281R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,ELISA

  • BN41281R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,ELISA

產(chǎn)品描述

英文名稱PPHLN1
中文名稱脈周蛋白1抗體（胃癌抗原蛋白Ga50）
別    名Gastric cancer antigen Ga50; Periphilin 1; Periphilin-1; PPHLN_HUMAN; PPHLN1.  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  細(xì)胞周期蛋白  細(xì)胞分化  細(xì)胞類型標(biāo)志物  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
細(xì)胞定位細(xì)胞核 細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PPHLN1:301-400/458 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.

Function:
Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.

Subunit:
Homodimer. Interacts with PPL.

Subcellular Location:
Nucleus. Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Substrate of transglutaminase (in vitro).

SWISS:
Q8NEY8

Gene ID:
51535

Database links:
 UniProtKB/Swiss-Prot: Q8NEY8.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].