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垂體瘤細(xì)胞凋亡抗體
  • 產(chǎn)品貨號(hào)：
    BN41257R
  • 中文名稱：
    垂體瘤細(xì)胞凋亡抗體
  • 英文名稱：
    Rabbit anti-RHBDD3 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41257R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41257R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱RHBDD3
中文名稱垂體瘤細(xì)胞凋亡抗體
別    名C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3.  
研究領(lǐng)域細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量40kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RHBDD3:151-250/386 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Similarity:
Contains 1 UBA domain

SWISS:
Q9Y3P4

Gene ID:
25807

Database links:

Entrez Gene: 25807 Human

Entrez Gene: 279766 Mouse

Entrez Gene: 289753 Rat

SwissProt: Q9Y3P4 Human

SwissProt: Q8BP97 Mouse

SwissProt: Q642B3 Rat

Unigene: 106730 Human

Unigene: 260866 Mouse

Unigene: 9606 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

RHBDD3分子是一個(gè)全新的TLR信號(hào)途徑的負(fù)向調(diào)控蛋白分子,是一個(gè)能夠顯著抑制自身免疫性疾病發(fā)生的效應(yīng)分子,RHBDD3控制機(jī)體避免發(fā)生過度的免疫應(yīng)答、防止自身免疫性疾病的發(fā)生具有重要意義。













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