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細(xì)胞表面蛋白CD232抗體
  • 產(chǎn)品貨號(hào)：
    BN41254R
  • 中文名稱：
    細(xì)胞表面蛋白CD232抗體
  • 英文名稱：
    Rabbit anti-PLXNC1/CD232 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41254R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN41254R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱PLXNC1/CD232
中文名稱細(xì)胞表面蛋白CD232抗體
別    名CD232; Plexin-C1; PLXC1_HUMAN; Plxnc1; Virus-encoded semaphorin protein receptor.   
研究領(lǐng)域細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞膜受體  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量172kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PLXNC1/CD232:681-780/1568 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]

Function:
Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8.

Subcellular Location:
Membrane.

Tissue Specificity:
Detected in heart, brain, lung, spleen and placenta.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the plexin family.
Contains 1 Sema domain.

SWISS:
O60486

Gene ID:
10154

Database links:

Entrez Gene: 10154 Human

Entrez Gene: 54712 Mouse

Omim: 604259 Human

SwissProt: O60486 Human

SwissProt: Q9QZC2 Mouse

Unigene: 584845 Human

Unigene: 256712 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.