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細(xì)胞間粘附分子5抗體
  • 產(chǎn)品貨號(hào)：
    BN41226R
  • 中文名稱：
    細(xì)胞間粘附分子5抗體
  • 英文名稱：
    Rabbit anti-ICAM5 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41226R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41226R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱ICAM5
中文名稱細(xì)胞間粘附分子5抗體
別    名ICAM5_HUMAN; ICAM5 precursor; Intercellular adhesion molecule 5; Intercellular adhesion molecule 5 precursor; Intercellular adhesion molecule 5, telencephalin; Telencephalin; TLCN; TLN.  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細(xì)胞粘附分子  細(xì)胞類型標(biāo)志物  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Pig, Cow, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量97kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ICAM5:501-600/924 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

Function:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.

Similarity:
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 9 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:
Q9UMF0

Gene ID:
7087

Database links:

Entrez Gene: 7087 Human

Entrez Gene: 15898 Mouse

Entrez Gene: 313785 Rat

Omim: 601852 Human

SwissProt: Q9UMF0 Human

SwissProt: Q60625 Mouse

Unigene: 465862 Human

Unigene: 59765 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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