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細(xì)胞色素b5抗體
  • 產(chǎn)品貨號(hào)：
    BN41042R
  • 中文名稱：
    細(xì)胞色素b5抗體
  • 英文名稱：
    Rabbit anti-Cytochrome b5 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41042R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41042R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱Cytochrome b5
中文名稱細(xì)胞色素b5抗體
別    名CYB 5; CYB 5A; CYB5; CYB5_HUMAN; CYB5A; Cytochrome b 5; Cytochrome b5 (microsomal); Cytochrome b5; Cytochrome b5 type A (microsomal); Cytochrome b5 type A; MCB 5; MCB5; Microsomal cytochrome b5; Microsomal cytochrome b5 type A; Type 1 cyt b5; CYB5A.   
研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  線粒體  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量15kDa
細(xì)胞定位細(xì)胞漿 細(xì)胞膜 線粒體
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Cytochrome b5:9-80/134 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Function:
Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.

Subcellular Location:
Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Isoform 2: Cytoplasm.

DISEASE:
Methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]: A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the cytochrome b5 family.
Contains 1 cytochrome b5 heme-binding domain.

SWISS:
P00167

Gene ID:
1528

Database links:

Entrez Gene: 1528 Human

Entrez Gene: 109672 Mouse

Entrez Gene: 64001 Rat

Omim: 250790 Human

Omim: 613218 Human

SwissProt: P00167 Human

SwissProt: P56395 Mouse

SwissProt: Q544Z9 Mouse

SwissProt: P00173 Rat

Unigene: 465413 Human

Unigene: 31018 Mouse

Unigene: 1055 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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