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磷酸化三羥基三甲基輔酶A還原酶抗體
  • 產品貨號：
    BN40992R
  • 中文名稱：
    磷酸化三羥基三甲基輔酶A還原酶抗體
  • 英文名稱：
    Rabbit anti-phospho-HMGCR (Ser872) Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40992R-100ul

    100ul

    ￥2470.00

    交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產品描述

英文名稱phospho-HMGCR (Ser872)
中文名稱磷酸化三羥基三甲基輔酶A還原酶抗體
別    名phospho-HMGCR (S872); HMGCR (phospho-Ser872); HMGCR (phospho S872); 3 hydroxy 3 methylglutaryl CoA reductase; 3 hydroxy 3 methylglutaryl Coenzyme A reductase; 3 hydroxymethylglutaryl CoA reductase; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); 3-hydroxy-3-methylglutaryl-coenzyme A reductase; 3H3M; HMDH_HUMAN; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; Hydroxymethylglutaryl CoA reductase; LDLCQ3; MGC103269; Red.  




產品類型磷酸化抗體 
研究領域腫瘤  細胞生物  免疫學  信號轉導  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Rabbit, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量97kDa
細胞定位細胞漿 細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated Synthesised phosphopeptide derived from human HMGCR around the phosphorylation site of Ser872:NR(p-S)KI 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.

Function:
This transmembrane glycoprotein is involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis.

Subunit:
Homodimer.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein.

Similarity:
Belongs to the HMG-CoA reductase family.

SWISS:
P04035

Gene ID:
3156

Database links:

Entrez Gene: 3156 Human

Entrez Gene: 15357 Mouse

Entrez Gene: 25675 Rat

Omim: 142910 Human

SwissProt: P04035 Human

SwissProt: Q01237 Mouse

SwissProt: P51639 Rat

Unigene: 628096 Human

Unigene: 643495 Human

Unigene: 316652 Mouse

Unigene: 9437 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.