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粒細(xì)胞-巨噬細(xì)胞克隆刺激因子抗體
  • 產(chǎn)品貨號：
    BN40964R
  • 中文名稱：
    粒細(xì)胞-巨噬細(xì)胞克隆刺激因子抗體
  • 英文名稱：
    Rabbit anti-GM-CSF Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價(jià)

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  • BN40964R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40964R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40964R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Pig(predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Recombinant protein) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱GM-CSF
中文名稱粒細(xì)胞-巨噬細(xì)胞克隆刺激因子抗體
別    名Granulocyte-Macrophage Colony Stimulating Factor; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; Colony stimulating factor; CSF 2; CSF Alpha; CSF; CSF2; Eosinophil Colony Stimulating Factor; GMCSF; Granulocyte Macrophage Colony Stimulating Factor; MGC131935; MGC138897; Molgramostin; Pluripoietin Alpha; Sargramostim; granulocyte-macrophage colony-stimulating factor precursor; CSF2_HUMAN.   




研究領(lǐng)域腫瘤  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  趨化因子  細(xì)胞表面分子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Recombinant protein)
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量14kDa
細(xì)胞定位分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GM-CSF:65-144/144 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008].

Function:
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Subunit:
Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.

Subcellular Location:
Secreted.

Similarity:
Belongs to the GM-CSF family.

SWISS:
P04141

Gene ID:
1437

Database links:

Entrez Gene: 1437 Human

Omim: 138960 Human

SwissProt: P04141 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

GM-CSF是血管內(nèi)皮細(xì)胞、單核細(xì)胞和成纖維細(xì)胞合成的糖蛋白。能促進(jìn)中性粒細(xì)胞成熟；刺激成熟的粒細(xì)胞從骨髓釋出；增強(qiáng)中性粒細(xì)胞趨化及吞噬功能。














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