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原癌基因M-ras抗體
  • 產(chǎn)品貨號：
    BN40731R
  • 中文名稱：
    原癌基因M-ras抗體
  • 英文名稱：
    Rabbit anti-MRas Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40731R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse,Rat 推薦應(yīng)用：WB

  • BN40731R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse,Rat 推薦應(yīng)用：WB

產(chǎn)品描述

英文名稱MRas
中文名稱原癌基因M-ras抗體
別    名M-RAS; M ras; muscle RAS oncogene homolog precursor; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; RRas3; XRas.  
研究領(lǐng)域腫瘤  細胞生物  免疫學  細胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat, 
產(chǎn)品應(yīng)用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
細胞定位細胞漿 細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse MRas:201-259/259 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.

Function:
May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).

Tissue Specificity:
Expression highly restricted to the brain and heart.

Similarity:
Belongs to the small GTPase superfamily. Ras family.

SWISS:
O08989

Gene ID:
17532

Database links:

Entrez Gene: 22808 Human

Entrez Gene: 17532 Mouse

Entrez Gene: 25482 Rat

Omim: 608435 Human

SwissProt: O14807 Human

SwissProt: O08989 Mouse

SwissProt: P97538 Rat

Unigene: 527021 Human

Unigene: 2045 Mouse

Unigene: 10641 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

M-ras癌變基因的表達產(chǎn)物Ras蛋白存在于多數(shù)腫瘤之中，目前是腫瘤研究較重要的蛋白之一.













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