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荷爾蒙敏感脂肪酶抗體
  • 產(chǎn)品貨號(hào)：
    BN40729R
  • 中文名稱：
    荷爾蒙敏感脂肪酶抗體
  • 英文名稱：
    Rabbit anti-HSL/LIPE Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40729R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Rat(predicted:Human,Mouse,Pig,Cow,Sheep) 推薦應(yīng)用：IHC-P

  • BN40729R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Rat(predicted:Human,Mouse,Pig,Cow,Sheep) 推薦應(yīng)用：IHC-P

產(chǎn)品描述

英文名稱HSL/LIPE
中文名稱荷爾蒙敏感脂肪酶抗體
別    名Hormone sensitive lipase; hormone-sensitive lipase; Hormone sensitive lipase testicular isoform; HSL; LHS; Lipase hormone sensitive; LIPE; Hormone-sensitive lipase; LIPS_HUMAN.  
研究領(lǐng)域心血管  免疫學(xué)  生長(zhǎng)因子和激素  糖尿病  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Rat,  (predicted: Human, Mouse, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用IHC-P=1:400-800 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量116kDa
細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HSL/LIPE :441-540/1076 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹HSL ( hormone- sensitive lipase ) is an enzyme involved in hydrolysis of stored triglycerides and fatty acids; important for regulation of energy homeostasis. It has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.

Function:
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

Subunit:
Interacts with PTRF in the adipocyte cytoplasm.

Subcellular Location:
Cell membrane. Membrane, caveola. Cytoplasm, cytosol.

Similarity:
Belongs to the 'GDXG' lipolytic enzyme family.

SWISS:
Q05469

Gene ID:
3991

Database links:

Entrez Gene: 3991 Human

Entrez Gene: 16890 Mouse

Entrez Gene: 25330 Rat

Omim: 151750 Human

SwissProt: Q05469 Human

SwissProt: Q6NSL7 Human

SwissProt: P54310 Mouse

SwissProt: P15304 Rat

Unigene: 656980 Human

Unigene: 158548 Mouse

Unigene: 333679 Mouse

Unigene: 10566 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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