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腦膠質(zhì)瘤發(fā)病機制相關(guān)蛋白1抗體
  • 產(chǎn)品貨號：
    BN40714R
  • 中文名稱：
    腦膠質(zhì)瘤發(fā)病機制相關(guān)蛋白1抗體
  • 英文名稱：
    Rabbit anti-GLIPR1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40714R-100ul

    100ul

    ￥2360.00

    交叉反應：Mouse 推薦應用：IHC-P

  • BN40714R-200ul

    200ul

    ￥3490.00

    交叉反應：Mouse 推薦應用：IHC-P

產(chǎn)品描述

英文名稱GLIPR1
中文名稱腦膠質(zhì)瘤發(fā)病機制相關(guān)蛋白1抗體
別    名ALKN2972; GLIPR1-like protein 1; MGC26856; PRO7434; UNQ2972/PRO7434; GLIPR; RTVP1; GliPR 1; Protein RTVP-1; Glioma pathogenesis-related protein 1; GLIP1_HUMAN.  
研究領(lǐng)域腫瘤  細胞生物  免疫學  發(fā)育生物學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse, 
產(chǎn)品應用IHC-P=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量27kDa
細胞定位細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse GLIPR1:11-110/255 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Subcellular Location:
Single-pass membrane protein.

Tissue Specificity:
According to PubMed:8973356, it is ubiquitously expressed with high levels in lung and kidney and low levels in heart and liver. Highly expressed in cell lines derived from nervous system tumors arising from glia, low or absent in non-glial-derived nervous system tumor cell lines. Also found in fetal kidney. According to PubMed:7607567 it is expressed only in brain tumor glioblastoma multiforme/astrocytoma and not in other nervous system tumors or normal fetal or adult tissues.

Similarity:
Belongs to the CRISP family.

SWISS:
Q9CWG1

Gene ID:
73690

Database links:

Entrez Gene: 11010 Human

Entrez Gene: 299783 Rat

Omim: 602692 Human

SwissProt: P48060 Human

Unigene: 205558 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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