最近搜索：細胞培養(yǎng) 微生物學 分子生物 生物化學
首頁>>免疫學>>一抗>>14號染色體開放閱讀框156抗體
14號染色體開放閱讀框156抗體
  • 產(chǎn)品貨號：
    BN40655R
  • 中文名稱：
    14號染色體開放閱讀框156抗體
  • 英文名稱：
    Rabbit anti-SLIRP/C14orf156 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40655R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse(predicted:Rat,Pig,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40655R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse(predicted:Rat,Pig,Rabbit) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱SLIRP/C14orf156
中文名稱14號染色體開放閱讀框156抗體
別    名C14orf156; Chromosome 14 open reading frame 156; DC50; DC23; PD04872; SLIRP; SRA stem loop interacting RNA binding protein, mitochondrial.  
研究領域細胞生物  信號轉(zhuǎn)導  生長因子和激素  結(jié)合蛋白  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse,  (predicted: Rat, Pig, Rabbit, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量12kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SLIRP/C14orf156:31-100/109 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]

Function:
RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.

Subcellular Location:
Mitochondrial and Nuclear; Predominantly mitochondrial.

Tissue Specificity:
Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q9GZT3

Gene ID:
81892

Database links:

Entrez Gene: 81892 Human

Omim: 610211 Human

SwissProt: Q9GZT3 Human

Unigene: 655105 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











image.png

image.png

image.png

image.png