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宮頸癌癌基因4抗體
  • 產(chǎn)品貨號：
    BN40575R
  • 中文名稱：
    宮頸癌癌基因4抗體
  • 英文名稱：
    Rabbit anti-RBMS1/Cervical cancer oncogene 4 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN40575R-100ul

    100ul

    ￥2360.00

    交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40575R-200ul

    200ul

    ￥3490.00

    交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱RBMS1/Cervical cancer oncogene 4
中文名稱宮頸癌癌基因4抗體
別    名c myc gene single strand binding protein 2; C2orf12; Cervical cancer oncogene 4; HCC 4; MSSP 2; MSSP 3; MSSP; MSSP-1; MSSP-2; MSSP-3; MSSP1; RBMS1; RBMS1_HUMAN; RNA binding motif, single stranded interacting protein 1; RNA-binding motif; SCR2; Single stranded DNA binding protein MSSP 1; Single-stranded DNA-binding protein MSSP-1; single-stranded-interacting protein 1; suppressor of cdc 2 (cdc13) with RNA binding motif 2; Suppressor of CDC2 with RNA binding motif 2; Suppressor of CDC2 with RNA-binding motif 2; YC1.  
研究領域腫瘤  細胞凋亡  細胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RBMS1/Cervical cancer oncogene 4:181-280/406 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]

Function:
Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highest amounts are found in placenta, lung and heart.

Similarity:
Contains 2 RRM (RNA recognition motif) domains.

SWISS:
P29558

Gene ID:
5937

Database links:

Entrez Gene: 395880 Chicken

Entrez Gene: 526135 Cow

Entrez Gene: 5937 Human

Entrez Gene: 56878 Mouse

Entrez Gene: 362138 Rat

GenBank: NP_058520.1 Human

Omim: 602310 Human

SwissProt: Q3ZBP3 Cow

SwissProt: P29558 Human

SwissProt: Q91W59 Mouse

SwissProt: Q5PQP1 Rat

Unigene: 470412 Human

Unigene: 708357 Human

Unigene: 259667 Mouse

Unigene: 482338 Mouse

Unigene: 98522 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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