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肝細(xì)胞核因子6抗體
  • 產(chǎn)品貨號(hào)：
    BN40508R
  • 中文名稱：
    肝細(xì)胞核因子6抗體
  • 英文名稱：
    Rabbit anti-HNF6 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40508R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Sheep) 推薦應(yīng)用：WB,ELISA

  • BN40508R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Sheep) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱HNF6
中文名稱肝細(xì)胞核因子6抗體
別    名hepatocyte nuclear factor 6 alpha; Hepatocyte nuclear factor 6; HNF 6; HNF-6; HNF6_HUMAN; HNF6A; One cut domain family member 1; One cut homeobox 1; Onecut1.  
研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  新陳代謝  表觀遺傳學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HNF6:351-465/465 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Function:
Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in liver; lower expression in testis and skin.

Similarity:
Belongs to the CUT homeobox family.
Contains 1 CUT DNA-binding domain.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q9UBC0

Gene ID:
3175

Database links:

Entrez Gene: 3175 Human

Entrez Gene: 15379 Mouse

Entrez Gene: 25231 Rat

Omim: 604164 Human

SwissProt: Q9UBC0 Human

SwissProt: O08755 Mouse

SwissProt: P70512 Rat

Unigene: 658573 Human

Unigene: 303355 Mouse

Unigene: 48812 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications