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轉(zhuǎn)錄因子Sp2抗體
  • 產(chǎn)品貨號：
    BN40505R
  • 中文名稱：
    轉(zhuǎn)錄因子Sp2抗體
  • 英文名稱：
    Rabbit anti-SP2 transcription factor Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN40505R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN40505R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱SP2 transcription factor
中文名稱轉(zhuǎn)錄因子Sp2抗體
別    名Kiaa0048; OTTHUMP00000196580; SP2; SP2_HUMAN; SPECIFICITY PROTEIN 2; Transcription factor Sp2.  
研究領域轉(zhuǎn)錄調(diào)節(jié)因子  結合蛋白  鋅指蛋白  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, 
產(chǎn)品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量65kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SP2 transcription factor:341-440/613 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]

Function:
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.

SWISS:
Q02086

Gene ID:
6668

Database links:

Entrez Gene: 6668 Human

Entrez Gene: 78912 Mouse

Omim: 601801 Human

SwissProt: Q02086 Human

SwissProt: Q9D2H6 Mouse

Unigene: 514276 Human

Unigene: 482333 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications