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G蛋白通路抑制物蛋白2抗體
  • 產(chǎn)品貨號(hào)：
    BN40456R
  • 中文名稱：
    G蛋白通路抑制物蛋白2抗體
  • 英文名稱：
    Rabbit anti-GPS2 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40456R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40456R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱GPS2
中文名稱G蛋白通路抑制物蛋白2抗體
別    名AMF-1; G protein pathway suppressor 2; GPS-2; GPS2; MGC104294; MGC119287; MGC119288; MGC119289; GPS2_HUMAN.  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  表觀遺傳學(xué)  G蛋白信號(hào)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量37kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GPS2:1-100/327 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]

Function:
Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.

Subunit:
Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2.

Tissue Specificity:
Widely expressed.

SWISS:
Q13227

Gene ID:
2874

Database links:

Entrez Gene: 2874 Human

SwissProt: Q13227 Human

Unigene: 438219 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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