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G蛋白偶聯(lián)嘌呤受體p2y8抗體
  • 產(chǎn)品貨號(hào)：
    BN40350R
  • 中文名稱：
    G蛋白偶聯(lián)嘌呤受體p2y8抗體
  • 英文名稱：
    Rabbit anti-P2Y8 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40350R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN40350R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱P2Y8
中文名稱G蛋白偶聯(lián)嘌呤受體p2y8抗體
別    名P2RY8; P2RY8_HUMAN; P2Y purinoceptor 8; P2Y8; Purinergic receptor P2Y G protein coupled 8.  
研究領(lǐng)域神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, 
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量41kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human P2Y8:131-230/359 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G-protein coupled receptors translate extracellular signals into intracellular signals (G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. P2RY8 (purinergic receptor P2Y, G-protein coupled, 8), also known as P2Y8, is a 359 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein-coupled receptor family. Expressed at low levels in lung, heart and kidney, P2RY8 may function as a receptor for purines that are coupled to G proteins and may also play a role in mental retardation.

Function:
Probable receptor for purines coupled to G-proteins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q86VZ1

Gene ID:
286530

Database links:

Entrez Gene: 286530 Human

Omim: 300525 Human

SwissProt: Q86VZ1 Human

Unigene: 111377 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.