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單氨氧化酶A+B抗體
  • 產(chǎn)品貨號(hào)：
    BN40335R
  • 中文名稱：
    單氨氧化酶A+B抗體
  • 英文名稱：
    Rabbit anti-Monoamine oxidase A+B Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40335R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN40335R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Monoamine oxidase A+B
中文名稱單氨氧化酶A+B抗體
別    名Adrenalin oxidase; AOFA_HUMAN; AOFB_HUMAN; Amine oxidase (flavin containing) A; Amine oxidase (flavin containing); Amine oxidase (flavin containing) B; Brunner syndrome; MAO A; MAO; MAO brain; MAO platelet; MAOA; MAOB; Monoamine oxidase A; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase type A; Monoamine oxidase type B; Tyramine oxidase.  
研究領(lǐng)域細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量60+59kDa
細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Monoamine oxidase A+B:131-230/527 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Monoamine oxidase A and B catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. MAOB preferentially degrades benzylamine and phenylethylamine

Function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

Subunit:
Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

Subcellular Location:
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.

Tissue Specificity:
Heart, liver, duodenum, blood vessels and kidney.

DISEASE:
Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior.

Similarity:
Belongs to the flavin monoamine oxidase family.

SWISS:
P21397 P27338

Gene ID:
4128 4129

Database links:
UniProtKB/Swiss-Prot: P21397.1 UniProtKB/Swiss-Prot: P27338.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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