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有脊椎動物腦發(fā)育相關蛋白Emx1抗體
  • 產品貨號：
    BN40332R
  • 中文名稱：
    有脊椎動物腦發(fā)育相關蛋白Emx1抗體
  • 英文名稱：
    Rabbit anti-Emx1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產品規(guī)格

    售價

    備注

  • BN40332R-100ul

    100ul

    ￥2360.00

    交叉反應：Human(predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN40332R-200ul

    200ul

    ￥3490.00

    交叉反應：Human(predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產品描述

英文名稱Emx1
中文名稱有脊椎動物腦發(fā)育相關蛋白Emx1抗體
別    名Empty spiracles homeobox 1; Empty spiracles homolog 1; empty spiracles homolog 1 Drosophila antibodyEmpty spiracles like protein 1; Empty spiracles-like protein 1; EMX1 ; EMX1_HUMAN ; Homeobox protein EMX1.  
研究領域細胞生物  發(fā)育生物學  神經生物學  信號轉導  干細胞  轉錄調節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量29kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Emx1:201-257/257 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹Emx1 and Emx2 are human homologs to the Drosophila developmental genes empty spiracles expressed in anterior body regions during early Drosophila embryogenesis. Emx1 and Emx2 are homeobox proteins expressed in the developing vertebrate brain. Emx2 is expressed in the dorsal telencephalon and small diencephalic regions, while Emx1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon. In the embryonic brain, Emx1 is expressed in both proliferating and differentiating neurons while Emx2 is expressed only in proliferating neurons. OTX1 and OTX2 are human homologs of the Drosophila developmental genes orthodenticle. In development, the sequence of expression begins with OTX2 at day 10 post coitum followed by OTX1, Emx2 and finally Emx1. The genes encoding human Emx1 and Emx2 map to chromosomes 2p14-p13 and 10q26.1, respectively.

Function:
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.

Subcellular Location:
Nucleus.

Tissue Specificity:
Cerebral cortex.

Similarity:
Belongs to the EMX homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q04741

Gene ID:
2016

Database links:

Entrez Gene: 2016 Human

Entrez Gene: 13796 Mouse

Entrez Gene: 500235 Rat

Omim: 600034 Human

SwissProt: Q04741 Human

SwissProt: Q04742 Mouse

Unigene: 516090 Human

Unigene: 391473 Mouse

Unigene: 140907 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.