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肝癌衍生生長因子/高遷移率族蛋白1樣蛋白2抗體
  • 產(chǎn)品貨號：
    BN40275R
  • 中文名稱：
    肝癌衍生生長因子/高遷移率族蛋白1樣蛋白2抗體
  • 英文名稱：
    Rabbit anti-HDGF Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40275R-100ul

    100ul

    ￥2360.00

    交叉反應：Human(predicted:Mouse,Rat,Pig,Cow,GuineaPig) 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN40275R-200ul

    200ul

    ￥3490.00

    交叉反應：Human(predicted:Mouse,Rat,Pig,Cow,GuineaPig) 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱HDGF
中文名稱肝癌衍生生長因子/高遷移率族蛋白1樣蛋白2抗體
別    名HDGF; HDGF_HUMAN; Hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1 like 2; High mobility group protein 1-like 2; HMG-1L2; HMG1L2.  
研究領域腫瘤  細胞生物  免疫學  腫瘤細胞生物標志物  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human,  (predicted: Mouse, Rat, Pig, Cow, Guinea Pig, )
產(chǎn)品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量27kDa
細胞定位細胞漿 細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HDGF:81-180/240 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.

Subunit:
Monomer, and domain-swapped homodimer.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.

Similarity:
Belongs to the HDGF family.
Contains 1 PWWP domain.

SWISS:
P51858

Gene ID:
3068

Database links:

Entrez Gene: 3068 Human

Entrez Gene: 15191 Mouse

Entrez Gene: 114499 Rat

Omim: 600339 Human

SwissProt: P51858 Human

SwissProt: P51859 Mouse

SwissProt: Q8VHK7 Rat

Unigene: 506748 Human

Unigene: 292208 Mouse

Unigene: 860 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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