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產(chǎn)品規(guī)格
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BN40242R-100ul
100ul
¥2360.00
交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF
BN40242R-200ul
200ul
¥3490.00
交叉反應(yīng):Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,ICC,IF
產(chǎn)品描述
英文名稱 | TBCEL |
中文名稱 | 微管蛋白折疊輔助因子E樣抗體 |
別 名 | EL; Leucine-rich repeat-containing protein 35; LRRC35; TBCEL; TBCEL_HUMAN; Tubulin folding cofactor E-like; Tubulin-specific chaperone cofactor E-like protein. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 48kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TBCEL:1-100/424 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
產(chǎn)品介紹 | TBCEL is a 424 amino acid cytoplasmic protein that acts as a regulator of tubulin stability. While abundantly expressed in testis, TBCEL is also present in several tissues at a much lower level. TBCEL contains seven LRR (leucine-rich) repeats, one LRRCT domain and one ubiquitin-like domain. The gene that encodes TBCEL consists of 66,704 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. Function: Acts as a regulator of tubulin stability. Subcellular Location: Cytoplasm > cytoskeleton. Tissue Specificity: Abundantly expressed in testis, but is also present in several tissues at a much lower level. Similarity: Contains 7 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 ubiquitin-like domain. SWISS: Q5QJ74 Gene ID: 219899 Database links: Entrez Gene: 219899 Human Omim: 610451 Human SwissProt: Q5QJ74 Human Unigene: 504136 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |